Cannabis use might be linked to structural changes to heart, according to the findings of a new study published in JACC Cardiovascular Imaging.
To conduct this study, researchers included 3,407 individuals (median age, 62, 55% female) of which, 47 currently used cannabis, 105 previously used cannabis, and 3,255 rarely, if ever, used cannabis. Current regular users were more likely to be younger, male, and current tobacco smokers and have greater levels of social deprivation compared with rare/never users and previous regular users. They were also less likely to be taking anti-hypertension medication.
The study results showed that regular cannabis use was associated with larger indexed left ventricular end diastolic volume (+5.31 ml/m2; 95% CI, 1.4 to 9.3 ml/m2; p = 0.008), end systolic volume (+3.3 ml/m2; 95% CI, 0.78 to 5.83 ml/m2; p = 0.010), and impaired global circumferential strain (−0.78; 95% CI: −1.47 to −0.09; p = 0.026) compared with rare/no cannabis use, even after adjusting for confounders such as age, sex, body mass index, systolic blood pressure, use of cholesterol medication, diabetes, smoking, and alcohol consumption.
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