A puzzling murmur reveals nonbacterial endocarditis in a cancer patient—underscoring echo limits and diagnostic nuance. Review iron deficiency in heart failure, key trials, guideline-based IV iron use, and strategies to improve patient outcomes. A case-based look at RV failure in PAH, covering diagnosis, ICU management, prognostication, and care planning. Learn key ARVC insights with a focus on genetics, imaging, risk assessment, and the role of genetic counseling in care. Deep dive into STEMI shock with Dr. Burkhoff, using PV loops and real-time hemodynamics to guide MCS decisions. Explore advanced PH management in left heart disease with Dr. Tedford, covering hemodynamics, meds, and MCS strategies. Learn practical GDMT tips in HFrEF with Dr. Randall Starling—case-based insights on meds, titration & hemodynamics. Chest pain in a 53-year-old leads to a surprising diagnosis: congenitally corrected transposition of the great arteries. Dr. Mark Drazner on why the bedside exam still matters in heart failure—insights you can’t get from labs alone. HFpEF in women needs holistic care targeting sex-specific risks, lifestyle, and novel therapies for better outcomes. Stimulant use can cause severe cardiomyopathy. Learn how “Heart Plus” bridges cardiology and addiction care. How do LVADs impact kidney function? Experts unpack the risks, benefits, and management of renal dysfunction in LVAD patients Challenging HFpEF cases? Learn diagnostic tips & guideline-based treatments from Dr. Jane Wilcox. OCT-derived virtual flow reserve predicts 2-year vessel failure post-PCI, adding physiologic insight to anatomic assessment. OCTIVUS shows PCI outcomes improve with EAPCI-defined stent optimization, regardless of imaging modality. MITT and safety data show acoramidis significantly lowers AFib-related events in transthyretin cardiac amyloidosis. LuX-Valve offers a safe, effective option for severe TR patients at high surgical risk. ESC 2025: Acoramidis may reduce AF/flutter burden in ATTR-CM, per new ATTRibute-CM trial analysis discussed by CardioNerds. CTA-first screening before TAVR avoids invasive angiography in 53% of patients—without compromising outcomes. Delays in TAVI for acute decompensated aortic stenosis worsen outcomes.